Entry id

1_oisrplpc

Hormone receptor positive, HER2 negative breast cancer is a spectrum disease, and we do have patients at particularly high risk for recurrence in the first 5 years. That is generally what we think about when we think about high-risk disease, at least initially in the clinic. And these are patients generally with larger cancers, nodes positive, particularly high nodal burden, 4 or more lymph nodes positive, but also grade 3 disease, or one of a high-risk score on one of our genomic signatures, so 21 gene or 70 gene signatures.