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Zepbound ® (tirzepatide) injection
2.5 mg/ 5 mg/ 7.5 mg/ 10 mg/ 12.5 mg/ 15 mg
This information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.
Can Zepbound™ (tirzepatide) be used in patients with a history of ketoacidosis or coma?
Tirzepatide has not been studied in patients with a history of diabetic ketoacidosis or coma.
See important safety information, including boxed warning, in the attached prescribing information.
Ketoacidosis
There is no information on the use of tirzepatide in people with a history of ketoacidosis or coma because patients were excluded from tirzepatide clinical trials if they had a history of ketoacidosis or hyperosmolar state/coma.
Enclosed Prescribing Information
Date of Last Review: January 01, 2024