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Zepbound ® (tirzepatide) injection
2.5 mg/ 5 mg/ 7.5 mg/ 10 mg/ 12.5 mg/ 15 mg
This information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.
Can Zepbound® (tirzepatide) be used with weight loss drugs?
There is no information on the use of tirzepatide with other products for weight management because these participants were excluded from Lilly studies.
See important safety information, including boxed warning, in the attached prescribing information.
Use With Weight Loss Medications
Use of weight loss drugs with tirzepatide has not been studied.
In tirzepatide clinical trials, participants were excluded if they had used prescription or over-the-counter drugs that promote weight loss within 3 months prior to the beginning of the study.1
Enclosed Prescribing Information
ZEPBOUND® (tirzepatide) injection, for subcutaneous use, Lilly
1. Data on file, Eli Lilly and Company and/or one of its subsidiaries.
Date of Last Review: November 10, 2025