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Jaypirca ® (pirtobrutinib) tablets
50 mg,100 mg
This information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.
Should Jaypirca® (pirtobrutinib) be dose-adjusted in hepatic impairment?
No dose modification is required in mild, moderate, or severe hepatic impairment.
Pirtobrutinib Pharmacokinetics in Healthy Subjects and Patients with Cancer
The pharmacokinetics of pirtobrutinib were characterized in healthy subjects and in patients with cancer.1
Does Hepatic Impairment Require Pirtobrutinib Dose Adjustment?
Use in Patients With Hepatic Impairment show dose adjustments of pirtobrutinib due to hepatic impairment.
Enclosed Prescribing Information
Reference
1Jaypirca [package insert]. Indianapolis, IN: Eli Lilly and Company; 2025.
Date of Last Review: October 08, 2025