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Cialis ® (tadalafil) tablets
2.5 mg, 5 mg, 10mg, 20 mg tablets
This information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.
What are the effects of skipping a dose of Cialis® (tadalafil)?
Clinical trials of tadalafil for the once-daily treatment of ED and/or signs and symptoms of BPH did not study the effect of skipping tadalafil doses.
This content was last updated on Oct 22, 2025. Literature published after this date may not be reflected in the content. Please refer to the, https://uspl.lilly.com/cialis/cialis.html, Medical.lilly.com and PubMed for additional information on this topic.
Impact on Efficacy
Tadalafil dosed once daily has been studied in clinical trials for the treatment of
- erectile dysfunction (ED)
- the signs and symptoms of benign prostatic hyperplasia (BPH), and
- both ED and the signs and symptoms of BPH.1
Once-daily dosing allows the achievement of steady-state plasma concentration, and clinical efficacy was assessed following daily dosing. The impact of a missed day of therapy has not been studied, but impact on efficacy is likely to vary by patient. Some patients may notice reduced efficacy from missing a single dose while others may not.2
Enclosed Prescribing Information
Reference
1Cialis [package insert]. Indianapolis, IN: Eli Lilly and Company; 2023.
2Data on file, Eli Lilly and Company and/or one of its subsidiaries.
Date of Last Review: October 22, 2025