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  1. Medical Information Right
  2. Immunology Right
  3. Omvoh (mirikizumab-mrkz) injection Right
  4. What if a patient only uses 1 pen or syringe (instead of the required 2 pens or syringes) for a maintenance dose of Omvoh® (mirikizumab-mrkz)?
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Omvoh ® (mirikizumab-mrkz) injection

300 mg/15 mL, 100 mg/mL

Full Prescribing Information

This information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.

What if a patient only uses 1 pen or syringe (instead of the required 2 pens or syringes) for a maintenance dose of Omvoh® (mirikizumab-mrkz)?

If a dose of Omvoh (mirikizumab) is missed, administer the dose as soon as possible. Thereafter, resume dosing every 4 weeks.

US_cFAQ_MIR217_ONLY_USED_ONE_SC_PEN_SYRINGE
US_cFAQ_MIR217_ONLY_USED_ONE_SC_PEN_SYRINGEen-US

Recommendations for Handling a Missed Maintenance Dose

Recommendations on How to Proceed With Dosing if Only One Prefilled Pen or Prefilled Syringe Was Injected provides recommendations for what to do in the event a patient only injects 1 prefilled pen or prefilled syringe for their maintenance dose (instead of 2 prefilled pens or 2 prefilled syringes which make up a full maintenance dose).1

Recommendations on How to Proceed With Dosing if Only One Prefilled Pen or Prefilled Syringe Was Injected1

If only one prefilled pen or prefilled syringe was injected and it has been...

Then it is recommended that the patient

less than 4 weeks since the last injection

inject the missed prefilled pen or prefilled syringe as soon as possible and continue every 4-week maintenance dosing.1

4 weeks or more since the last injection

skip the missed prefilled pen or prefilled syringe and resume scheduled maintenance dosing with 2 prefilled pens or 2 prefilled syringes every 4 weeks.1

What if the Patient Has Only Injected 1 Prefilled Pen or 1 Prefilled Syringe for a Single Past Maintenance Dose?

The patient should resume scheduled maintenance dosing with 2 prefilled pens or 2 prefilled syringes every 4 weeks.1

What if the Patient Has Only Been Injecting 1 Prefilled Pen or 1 Prefilled Syringe for Multiple Past Maintenance Doses?

Maintenance doses below 200 mg may lead to decreased efficacy.2

The patient should resume scheduled maintenance dosing with 2 prefilled pens or 2 prefilled syringes every 4 weeks.1

Enclosed Prescribing Information

OMVOH® (mirikizumab-mrkz) injection, for intravenous or subcutaneous use, Lilly

References

1Omvoh [package insert]. Indianapolis, IN: Eli Lilly and Company; 2025.

2Data on file, Eli Lilly and Company and/or one of its subsidiaries.

Date of Last Review: February 21, 2025

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