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Cialis ® (tadalafil) tablets
2.5 mg, 5 mg, 10mg, 20 mg tablets
This information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.
What is the recommended dose of Cialis® (tadalafil) for use in patients with hepatic impairment?
Caution should be exercised when prescribing Cialis® (tadalafil) to patients with severe hepatic impairment.
Dosing With Hepatic Impairment
Tadalafil use in patients with hepatic impairment for treatment of erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and ED/BPH is seen in Tadalafil Dosing and Administration for Erectile Dysfunction in Patients With Hepatic Impairment and Tadalafil Dosing and Administration for Benign Prostatic Hyperplasia and for Erectile Dysfunction and Benign Prostatic Hyperplasia.
Dosing and Administration |
Tadalafil for Use As Needed |
Tadalafil for Once-Daily Use |
Hepatic impairment (mild to moderate)a |
Not to exceed 10 mg once per day. The use of tadalafil once per day has not been extensively evaluated; caution advised if prescribed. |
The use of tadalafil once per day has not been extensively evaluated; caution advised if prescribed. |
Hepatic impairment (severe)a |
Use is NOT recommended. |
Use is NOT recommended. |
a Hepatic impairment: mild or moderate=Child-Pugh class A or B; severe=Child-Pugh class C.
Dosing and Administration |
Tadalafil for BPH |
Tadalafil for ED and BPH |
Hepatic impairment (mild to moderate)a |
The use of tadalafil once per day has not been extensively evaluated; caution advised if prescribed. |
The use of tadalafil once per day has not been extensively evaluated; caution advised if prescribed. |
Hepatic impairment (severe)a |
Use is NOT recommended. |
Use is NOT recommended. |
Abbreviations: BPH = benign prostatic hyperplasia; ED = erectile dysfunction.
a Hepatic impairment: mild or moderate=Child-Pugh class A or B; severe=Child-Pugh class C.
Enclosed Prescribing Information
Reference
1Cialis [package insert]. Indianapolis, IN: Eli Lilly and Company; 2018.
Date of Last Review: April 25, 2023