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Welcome to Lilly Scientific Information Page for CTAD 2025

Clinical Trials on Alzheimer's Disease

location-single Group San Diego, California

Calendar December 1, 2025 - December 4, 2025
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Disclosures

MONDAY

DECEMBER 1, 2025, 3:00 p.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Hong Wang
  • Molecule(s): Donanemab

The Effect of Corticosteroid Pre-Treatment with Modified Titration of Donanemab on Amyloid Reduction and Safety: TRAILBLAZER-ALZ 6 Addendum Design

Trial(s) Overview:

TRAILBLAZER-ALZ 6

Poster

MONDAY

DECEMBER 1, 2025, 3:00 p.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Matthew Hufford
  • Molecule(s): Remternetug

Feasibility of Participants with Symptomatic Alzheimer's Disease to Self-Administer Remternetug Subcutaneously: Results from the TRAILRUNNER-ALZ 1 Phase 3 Trial

Trial(s) Overview:

TRAILRUNNER-ALZ 1

Poster

MONDAY

DECEMBER 1, 2025, 3:00 p.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Paul Ardayfio
  • Molecule(s): Donanemab

Baseline use of Antihypertensive Medication is Associated with Reduced Frequency of Amyloid-Related Imaging Abnormalities-Edema with Donanemab: Results from the TRAILBLAZER Randomized Clinical Trials

Trial(s) Overview:

TRAILBLAZER-ALZ 1

TRAILBLAZER-ALZ 2

Poster

MONDAY

DECEMBER 1, 2025, 4:20 p.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Leanne Munsie
  • Molecule(s): Ceperognastat

Clinical, Safety, and Biomarker Outcomes From a Posttreatment Observational Extension of the Phase 2 PROSPECT-ALZ Study of Ceperognastat in Early Symptomatic Alzheimer’s Disease

Trial(s) Overview:

PROSPECT-ALZ

Presentation

WEDNESDAY

DECEMBER 3, 2025, 7:15 a.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Rose Beck
  • Molecule(s): Lilly SPX P-tau217 Assay

P-tau217 Testing Impact on Patient Management in a Racially/Ethnically Diverse Population: Six-Month Follow up in a Randomized Clinical Utility Study

Trial(s) Overview:

Not Applicable

Poster

WEDNESDAY

DECEMBER 3, 2025, 7:15 a.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Roy Yaari
  • Molecule(s): Solanezumab

Prognostic Models for Development of Elevated Plasma P-tau217 in Preclinical Alzheimer’s Disease: Insights from A4/LEARN

Trial(s) Overview:

A4/LEARN

Poster

WEDNESDAY

DECEMBER 3, 2025, 9:30 a.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Ron DeMattos
  • Molecule(s): Not Applicable

Next Generation Anti-Amyloid Therapies ...Shuttling Past the ARIA Risk

Trial(s) Overview:

Not Applicable

Presentation

WEDNESDAY

DECEMBER 3, 2025, 9:55 a.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Diana Svaldi
  • Molecule(s): Donanemab

Head-to-Head Comparison of SWI and T2*-Weighted Gradient Echo MRI Sequences to Detect ​ARIA-H in the TRAILBLAZER-ALZ 6 Trial of Donanemab

Trial(s) Overview:

TRAILBLAZER-ALZ 6

Presentation

WEDNESDAY

DECEMBER 3, 2025, 4:20 p.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Jennifer Zimmer
  • Molecule(s): Donanemab

Donanemab in Early Symptomatic Alzheimer's Disease: Additional Insights from the TRAILBLAZER‐ALZ 2 Long-Term Extension

Trial(s) Overview:

TRAILBLAZER-ALZ 2

Presentation

THURSDAY

DECEMBER 4, 2025, 7:15 a.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Diego Novick
  • Molecule(s): Not Applicable

Cognitive Trajectories in Alzheimer's Disease: Findings from the Multinational CICERO-AD Chart Review Study

Trial(s) Overview:

CICERO-AD (Not a clinical trial)

Poster

THURSDAY

DECEMBER 4, 2025, 7:15 a.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Eric Klein
  • Molecule(s): Not Applicable

Impact of Telemedicine on Time and Process Measures Associated with Detection and Diagnosis of Alzheimer's Disease

Trial(s) Overview:

Not Applicable

Poster

THURSDAY

DECEMBER 4, 2025, 7:15 a.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Nalin Payakachat
  • Molecule(s): Solanezumab

Development of Prognostic Models for Five-Year Risk of Clinical Progression from Preclinical Alzheimer’s Disease (Stage 1 and 2) to Cognitive Impairment: Findings from the A4 Study​

Trial(s) Overview:

A4/LEARN

Poster

THURSDAY

DECEMBER 4, 2025, 7:15 a.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Oralee Varnado
  • Molecule(s): Not Applicable

Neurologists’ Perceptions and Experiences with Amyloid-Targeting Therapies in Alzheimer’s Disease in the United States: Baseline Data

Trial(s) Overview:

Not Applicable

Poster

THURSDAY

DECEMBER 4, 2025, 11:00 a.m PST
  • Disease State: Alzheimer's Disease
  • Presented by: Karen Holdridge
  • Molecule(s): Donanemab

Recruitment and Screening in TRAILBLAZER-ALZ 3: A Decentralized Study of Donanemab in Preclinical Alzheimer’s Disease

Trial(s) Overview:

TRAILBLAZER-ALZ 3

Presentation

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