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Oncology Journal Publications

This page includes links to Lilly sponsored trials and observational research that have been published in peer reviewed journals within the last 5 years. Each section is sorted by product and may be expanded for more information. The list of publications below is limited to products that have been approved for use and may contain information about doses, delivery devices, uses, formulations and populations different from product labeling. Clinical decisions should be based on the full safety and efficacy information contained in the product's Full Prescribing Information in the provided link below.

If you have questions about a Lilly study not listed below or would like to request an electronic copy of one of the journal publications on this page, please call 1-800-LILLYRX (1-800-545-5979). For our publication linking statement click here.

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Cyramza® (ramucirumab)

Full Prescribing Information

Final Survival Outcomes With Ramucirumab Plus Erlotinib Versus Placebo Plus Erlotinib in Patients With Untreated EGFR-Mutated Metastatic NSCLC: RELAY Japanese Subset
Published Date: November 30, 2024
RELAY, Erlotinib Plus Ramucirumab in Untreated, EGFR-Mutated, Metastatic NSCLC: Outcomes by EGFR Exon 19 Deletion Variants
Published Date: December 19, 2023
Bayesian Survival Extrapolation for Cost effectiveness analysis: a case study of RELAY for ramucirumab in combination with erlotinib in the treatment of non-small-cell lung cancer
Published Date: October 16, 2023
Impact of ramucirumab plus erlotinib on circulating cell-free DNA from patients with untreated metastatic non-small cell lung cancer with EGFR-activating mutations (RELAY phase 3 randomized study).
Published Date: September 7, 2023
RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in previously untreated EGFR mutation-positive metastatic NSCLC: Exploratory analysis of next-generation sequencing results
Published Date: August 1, 2023
Efficacy and tolerability of ramucirumab plus erlotinib in Taiwanese patients with untreated, epidermal growth factor receptor-mutated stage IV non-small-cell lung cancer in the RELAY study
Published Date: June 17, 2023
RELAY, Ramucirumab plus Erlotinib (RAM+ERL) in Untreated Metastatic EGFR-Mutant NSCLC (EGFR+ NSCLC): Association between TP53 Status and Clinical Outcome
Published Date: March 27, 2023
RELAY, Ramucirumab plus Erlotinib versus Placebo plus Erlotinib in Untreated EGFR-Mutated Metastatic Non-Small Cell Lung Cancer: Exposure-Response Relationship
Published Date: July 16, 2022
RELAY+: Exploratory Study of Ramucirumab Plus Gefitinib in Untreated Patients With EGFR-Mutated Metastatic NSCLC
Published Date: March 28, 2022
RELAY: Clinical and Next-Generation Sequencing Analyses of Ex19del and Ex21L858R Mutation Subgroups in Untreated, EGFR-Mutated, Metastatic Non-small Cell Lung Cancer
Published Date: January 3, 2022
RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in patients with untreated, epidermal growth factor receptor mutation-positive, metastatic non-small cell lung cancer: long-term toxicity and resource use
Published Date: January 3, 2022
RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in patients with untreated, EGFR-mutated, metastatic non-small cell lung cancer: Europe/United States subset analysis.
Published Date: June 29, 2021

Evaluating alternative ramucirumab doses as single agent or with paclitaxel in second-line treatment of locally advanced or metastatic gastric/gastroesophageal junction adenocarcinoma: results from 2 randomized, open-label, phase II studies
Published Date: February 24, 2022

RELAY: Safety and efficacy of ramucirumab plus erlotinib in elderly Japanese patients with metastatic EGFR-mutated NSCLC
Published Date: November 4, 2025
RELAY+: Final Overall Survival With Ramucirumab Plus Gefitinib in Patients With Untreated EGFR-Mutated Metastatic NSCLC
Published Date: September 26, 2025
Final Survival Outcomes With Ramucirumab Plus Erlotinib Versus Placebo Plus Erlotinib in Patients With Untreated EGFR-Mutated Metastatic NSCLC: RELAY Japanese Subset
Published Date: November 30, 2024
RELAY, Erlotinib Plus Ramucirumab in Untreated, EGFR-Mutated, Metastatic NSCLC: Outcomes by EGFR Exon 19 Deletion Variants
Published Date: December 19, 2023
Bayesian Survival Extrapolation for Cost effectiveness analysis: a case study of RELAY for ramucirumab in combination with erlotinib in the treatment of non-small-cell lung cancer
Published Date: October 16, 2023
Impact of ramucirumab plus erlotinib on circulating cell-free DNA from patients with untreated metastatic non-small cell lung cancer with EGFR-activating mutations (RELAY phase 3 randomized study).
Published Date: September 7, 2023
RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in previously untreated EGFR mutation-positive metastatic NSCLC: Exploratory analysis of next-generation sequencing results
Published Date: August 1, 2023
Efficacy and tolerability of ramucirumab plus erlotinib in Taiwanese patients with untreated, epidermal growth factor receptor-mutated stage IV non-small-cell lung cancer in the RELAY study
Published Date: June 17, 2023
RELAY, Ramucirumab plus Erlotinib (RAM+ERL) in Untreated Metastatic EGFR-Mutant NSCLC (EGFR+ NSCLC): Association between TP53 Status and Clinical Outcome
Published Date: March 27, 2023
Exploratory Analysis of Patients With Gastric/Gastroesophageal Junction Adenocarcinoma With or Without Liver Metastasis From the Phase 3 RAINBOW Study
Published Date: March 20, 2023
Ramucirumab as second-line treatment in Chinese patients with advanced hepatocellular carcinoma and elevated alpha-fetoprotein after sorafenib (REACH-2 China): A randomised, multicentre, double-blind study.
Published Date: October 10, 2022
Ramucirumab for patients with advanced hepatocellular carcinoma and elevated alpha fetoprotein following a non-sorafenib based systemic therapy: Final results from an expansion cohort of the phase 3 REACH-2 study
Published Date: October 6, 2022
RELAY, Ramucirumab plus Erlotinib versus Placebo plus Erlotinib in Untreated EGFR-Mutated Metastatic Non-Small Cell Lung Cancer: Exposure-Response Relationship
Published Date: July 16, 2022
Prognostic and predictive factors in patients with advanced HCC and elevated alpha-fetoprotein treated with ramucirumab in two randomized Phase III trials
Published Date: April 20, 2022
Predictive biomarkers for survival benefit with ramucirumab in urothelial cancer in the RANGE trial
Published Date: April 6, 2022
RELAY+: Exploratory Study of Ramucirumab Plus Gefitinib in Untreated Patients With EGFR-Mutated Metastatic NSCLC
Published Date: March 28, 2022
The exposure-response relationship of ramucirumab in the RANGE randomized phase III trial of patients with advanced urothelial carcinoma refractory to platinum therapy
Published Date: January 13, 2022
RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in patients with untreated, epidermal growth factor receptor mutation-positive, metastatic non-small cell lung cancer: long-term toxicity and resource use
Published Date: January 3, 2022
RELAY: Clinical and Next-Generation Sequencing Analyses of Ex19del and Ex21L858R Mutation Subgroups in Untreated, EGFR-Mutated, Metastatic Non-small Cell Lung Cancer
Published Date: January 3, 2022
A multicenter, double-blind, randomized phase III trial of ramucirumab plus docetaxel versus placebo plus docetaxel for treatment of Stage IV non-small cell lung cancer after disease progression on or after platinum-based therapy (REVEL): An Indian patient subgroup analysis
Published Date: January 1, 2022
Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW-Asia): a double-blind, randomised phase 3 trial
Published Date: October 7, 2021
Ramucirumab for patients with intermediate-stage hepatocellular carcinoma (HCC) and elevated alpha fetoprotein (AFP): pooled results from two phase 3 studies (REACH and REACH-2)
Published Date: August 25, 2021
Clinical Development and Evaluation of a VEGF-D Assay in Plasma from Patients with Metastatic Colorectal Cancer in the RAISE Study
Published Date: July 28, 2021
RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in patients with untreated, EGFR-mutated, metastatic non-small cell lung cancer: Europe/United States subset analysis.
Published Date: June 29, 2021
Ramucirumab in patients with previously treated advanced hepatocellular carcinoma: Impact of liver disease aetiology
Published Date: June 26, 2021

Patient Characteristics, Testing and Treatment Patterns, and Outcomes in EGFR-mutated Advanced Non-Small Cell Lung Cancer: A Multinational, Real-World Study
Published Date: May 25, 2023
Real-world ramucirumab and immune checkpoint inhibitor sequences in US patients with advanced gastroesophageal cancer
Published Date: May 17, 2023
Post-Marketing Safety Study of Ramucirumab Plus FOLFIRI: Analysis of Age and Initial Dose of Irinotecan in Patients with Metastatic Colorectal Cancer.
Published Date: April 27, 2023
Real-world Molecular Biomarker Testing Patterns and Results for Advanced Gastroesophageal Cancers in the United States
Published Date: February 23, 2023
Risk Thresholds for Patients to Switch Between Daily Tablets and Biweekly Infusions in Second-Line Treatment for Advanced Hepatocellular Carcinoma: a Patient Preference Study
Published Date: January 19, 2023
TP53 Co-Mutation Status Association with Clinical Outcomes in Patients with EGFR-Mutant Non-Small Cell Lung Cancer
Published Date: December 12, 2022
Efficacy and safety of first-line therapies in EGFR-mutated advanced non-small-cell lung cancer: a network meta-analysis.
Published Date: February 23, 2022
Study of patient characteristics, treatment patterns, EGFR testing patterns and outcomes in real-world patients with EGFRm+ NSCLC
Published Date: October 12, 2021

Erbitux® (cetuximab)

Full Prescribing Information

No Publication Journals

No Publication Journals

Efficacy and safety of cetuximab dosing (biweekly vs weekly) in patients with KRAS wild-type metastatic colorectal cancer: A meta-analysis.
Published Date: February 19, 2022

No Publication Journals

Inluriyo™ (imlunestrant)

Full Prescribing Information

Disposition and Absolute Bioavailability of Oral Imlunestrant in Healthy Women: A Phase 1, Open-Label Study.
Published Date: June 24, 2025
Identification of a Safe and Tolerable Carbamazepine Dosing Paradigm that Facilitates Effective Evaluation of CYP3A4 Induction.
Published Date: June 10, 2024
Phase 1 Study Evaluating the Effect of Food and Omeprazole-Induced Gastric pH Change on the Pharmacokinetics and Safety of Imlunestrant in Healthy Females.
Published Date: November 21, 2025
Imlunestrant, an oral selective estrogen receptor degrader, as monotherapy and combined with abemaciclib, in recurrent/advanced ER-positive endometrioid endometrial cancer: results from the phase 1a/1b EMBER study
Published Date: October 22, 2024
Imlunestrant, an oral selective estrogen receptor degrader, in combination with HER2 directed therapy, with or without abemaciclib, in ER-positive, HER2-positive advanced breast cancer: results from the phase 1a/1b EMBER study.
Published Date: December 21, 2025
A Preoperative Window-of-Opportunity Study of Oral SERD, Imlunestrant, in Newly Diagnosed ER-Positive, HER2-Negative Early Breast Cancer: Results from the EMBER-2 Study.
Published Date: October 7, 2024

No Publication Journals

Imlunestrant with or without Abemaciclib in Advanced Breast Cancer
Published Date: December 13, 2024
Imlunestrant with or without Abemaciclib in Advanced Breast Cancer: Updated Efficacy Results from the phase 3 EMBER-3 trial
Published Date: December 12, 2025
Patient-reported outcomes and qualitative interviews in patients with estrogen receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: results from the phase III EMBER-3 trial
Published Date: April 1, 2025

No Publication Journals

Jaypirca® (pirtobrutinib)

Full Prescribing Information

Pirtobrutinib in Chinese patients with relapsed or refractory B-cell malignancies: A single-arm, open-label, phase 2, multicenter trial.
Published Date: February 28, 2025
Phase 1/2 BRUIN Trial Results of Pirtobrutinib Monotherapy in BTK Inhibitor Intolerant Patients with B-cell Malignancies
Published Date: January 6, 2025
Evaluation of Bleeding Risk in Patients Who Received Pirtobrutinib in the Presence or Absence of Antithrombotic Therapy
Published Date: September 27, 2024
Pirtobrutinib, a highly selective, non-covalent (reversible) BTK inhibitor in patients with B-cell malignancies: analysis of the Richter transformation subgroup from the multicentre, open-label, phase 1/2 BRUIN study.
Published Date: July 18, 2024
Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia.
Published Date: July 6, 2023
Pirtobrutinib in Covalent Bruton Tyrosine Kinase Inhibitor Pretreated Mantle-Cell Lymphoma.
Published Date: May 16, 2023
Pirtobrutinib preclinical characterization: a highly selective, non-covalent (reversible) BTK inhibitor
Published Date: February 17, 2023

Pirtobrutinib, a Highly Selective, Non-covalent (Reversible) BTK Inhibitor in Relapsed Marginal Zone Lymphoma: Phase 1/2 BRUIN Study
Published Date: January 17, 2026
Genomic Determinants of Response and Resistance to Pirtobrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia.
Published Date: October 8, 2025
Pirtobrutinib in Chinese patients with relapsed or refractory B-cell malignancies: A single-arm, open-label, phase 2, multicenter trial.
Published Date: February 28, 2025
Phase 1/2 BRUIN Trial Results of Pirtobrutinib Monotherapy in BTK Inhibitor Intolerant Patients with B-cell Malignancies
Published Date: January 6, 2025
Evaluation of Bleeding Risk in Patients Who Received Pirtobrutinib in the Presence or Absence of Antithrombotic Therapy
Published Date: September 27, 2024
Pirtobrutinib, a highly selective, non-covalent (reversible) BTK inhibitor in patients with B-cell malignancies: analysis of the Richter transformation subgroup from the multicentre, open-label, phase 1/2 BRUIN study.
Published Date: July 18, 2024
Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia.
Published Date: July 6, 2023
Pirtobrutinib in Covalent Bruton Tyrosine Kinase Inhibitor Pretreated Mantle-Cell Lymphoma.
Published Date: May 16, 2023
Pirtobrutinib preclinical characterization: a highly selective, non-covalent (reversible) BTK inhibitor
Published Date: February 17, 2023

Efficacy of Pirtobrutinib Monotherapy in Treatment-Naïve Chronic Lymphocytic Leukemia: A Bayesian Network Meta-Analysis of Randomized Controlled Trials
Published Date: February 11, 2026
BRUIN CLL-313: Randomized Phase III Trial of Pirtobrutinib Versus Bendamustine Plus Rituximab in Untreated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
Published Date: December 9, 2025
Pirtobrutinib Versus Ibrutinib in Treatment-Naïve and Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
Published Date: December 7, 2025
Phase III Trial of Pirtobrutinib Versus Idelalisib/Rituximab or Bendamustine/Rituximab in Covalent Bruton Tyrosine Kinase Inhibitor-Pretreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-321).
Published Date: June 6, 2025
BRUIN MCL-321: phase III study of pirtobrutinib versus investigator choice of BTK inhibitor in BTK inhibitor Naïve mantle cell lymphoma.
Published Date: November 15, 2022

Real-world treatment patterns, patient characteristics, and outcomes of initial cBTKi-based therapies in second-line or later amongst a contemporary cohort of patients with MCL in the United States
Published Date: February 24, 2026
Continuity of care for patients with chronic lymphocytic leukemia: an analysis of real-world data
Published Date: September 15, 2025
Disease management landscape in patients with mantle cell lymphoma in Japan: a real-world study
Published Date: September 9, 2025
Overall Survival Associated with Real-World Treatment Sequences in Patients with CLL/SLL in the United States
Published Date: August 7, 2025
Real-world outcomes after discontinuation of covalent BTK inhibitor-based therapy in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma
Published Date: March 23, 2025
Clinical trial participation, clinical care, and patient outcomes by practice setting: a real-world database analysis of patients with Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma
Published Date: February 5, 2025
Racial and Ethnic Characteristics and Outcomes of Patients Diagnosed with CLL/SLL in the USA
Published Date: May 28, 2024
Clinical outcomes among patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) who received treatment with a covalent BTK and BCL2 inhibitor in the United States: a real-world database study
Published Date: April 16, 2023
Outcomes Among Patients with Mantle Cell Lymphoma post-covalent BTK Inhibitor Therapy in the United States: A Real-World Electronic Medical Records Study
Published Date: December 28, 2022
Outcomes for Patients With Chronic Lymphocytic Leukemia (CLL) Previously Treated With Both a Covalent BTK and BCL2 Inhibitor in the United States: A Real-World Database Study
Published Date: November 8, 2022

Retevmo® (selpercatinib)

Full Prescribing Information

Population Pharmacokinetics Modeling of Selpercatinib to Support Posology in Pediatric Patients With RET-Altered Metastatic Thyroid Cancer or Solid Tumors.
Published Date: May 15, 2025
Long-term Safety of Selpercatinib for RET-activated Advanced Solid Tumors in LIBRETTO-001
Published Date: November 15, 2024
Durability of Response With Selpercatinib in Patients With RET-Activated Thyroid Cancer: Long-Term Safety and Efficacy From LIBRETTO-001.
Published Date: August 2, 2024
Patient-reported outcomes with selpercatinib treatment in patients with RET-driven cancers in the phase I/II LIBRETTO-001 trial
Published Date: May 14, 2024
Comparative Effectiveness of First-Line Selpercatinib versus Standard Therapies in Patients with RET-Activated Cancers: An Exploratory Interpatient Analysis of LIBRETTO-001
Published Date: December 27, 2023
Case Report: Complete pathologic response to neoadjuvant selpercatinib in a patient with resectable early-stage RET fusion-positive non-small cell lung cancer.
Published Date: May 18, 2023
Selpercatinib in Patients With RET Fusion-Positive Non-Small-Cell Lung Cancer: Updated Safety and Efficacy From the Registrational LIBRETTO-001 Phase I/II Trial
Published Date: September 19, 2022
Patient-Reported Outcomes with Selpercatinib Among Patients with RET Fusion-Positive Non-Small Cell Lung Cancer in the Phase I/II LIBRETTO-001 Trial.
Published Date: September 15, 2021
NTRK and RET fusion-directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake.
Published Date: September 15, 2021
Patient-Reported Outcomes with Selpercatinib Treatment Among Patients with RET-Mutant Medullary Thyroid Cancer in the Phase 1/2 LIBRETTO-001Trial
Published Date: September 13, 2021

Population Pharmacokinetics Modeling of Selpercatinib to Support Posology in Pediatric Patients With RET-Altered Metastatic Thyroid Cancer or Solid Tumors.
Published Date: May 15, 2025
Long-term Safety of Selpercatinib for RET-activated Advanced Solid Tumors in LIBRETTO-001
Published Date: November 15, 2024
Durability of Response With Selpercatinib in Patients With RET-Activated Thyroid Cancer: Long-Term Safety and Efficacy From LIBRETTO-001.
Published Date: August 2, 2024
Patient-reported outcomes with selpercatinib treatment in patients with RET-driven cancers in the phase I/II LIBRETTO-001 trial
Published Date: May 14, 2024
Comparative Effectiveness of First-Line Selpercatinib versus Standard Therapies in Patients with RET-Activated Cancers: An Exploratory Interpatient Analysis of LIBRETTO-001
Published Date: December 27, 2023
Intracranial Activity of Selpercatinib in Chinese Patients With Advanced RET Fusion-Positive Non-Small-Cell Lung Cancer in the Phase II LIBRETTO-321 Trial.
Published Date: June 15, 2023
Selpercatinib Monotherapy for RET Fusion/EGFR Co-Mutated Non-Small Cell Lung Cancer: A Case from the Phase II LIBRETTO-321 Study in Chinese Patients
Published Date: June 4, 2023
Case Report: Complete pathologic response to neoadjuvant selpercatinib in a patient with resectable early-stage RET fusion-positive non-small cell lung cancer.
Published Date: May 18, 2023
Selpercatinib in Patients With RET Fusion-Positive Non-Small-Cell Lung Cancer: Updated Safety and Efficacy From the Registrational LIBRETTO-001 Phase I/II Trial
Published Date: September 19, 2022
Tumour-agnostic efficacy and safety of selpercatinib in patients with RET fusion-positive solid tumours other than lung or thyroid tumours (LIBRETTO-001): a phase 1/2, open-label, basket trial
Published Date: September 12, 2022
Efficacy and safety of selpercatinib in Chinese patients with advanced RET fusion-positive non-small-cell lung cancer: a phase II clinical trial (LIBRETTO-321)
Published Date: September 6, 2022
Patient-Reported Outcomes with Selpercatinib Among Patients with RET Fusion-Positive Non-Small Cell Lung Cancer in the Phase I/II LIBRETTO-001 Trial.
Published Date: September 15, 2021
Patient-Reported Outcomes with Selpercatinib Treatment Among Patients with RET-Mutant Medullary Thyroid Cancer in the Phase 1/2 LIBRETTO-001Trial
Published Date: September 13, 2021

Patient-Reported Tolerability of Selpercatinib Compared to Cabozantinib/Vandetanib: A Secondary Analysis of the LIBRETTO-531 Randomized-Controlled Trial in RET-Mutant Medullary Thyroid Cancer | Thyroid®
Published Date: October 10, 2025
First-line Selpercatinib or Chemotherapy and Pembrolizumab in Patients From East Asia With RET Fusion-Positive NSCLC: A LIBRETTO-431 Subgroup Analysis.
Published Date: July 21, 2025
Patient-Reported Outcomes (PROs) from LIBRETTO-431: First-Line Selpercatinib versus Chemotherapy With Pembrolizumab in RET Fusion-positive NSCLC
Published Date: June 17, 2025
Selpercatinib in Chinese patients with RET-fusion-positive non-small-cell lung cancer: updated efficacy and safety analysis from the randomized LIBRETTO-321 phase II trial
Published Date: January 1, 2025
CNS Protective Effect of Selpercatinib in First-Line RET Fusion-Positive Advanced Non-Small Cell Lung Cancer.
Published Date: June 3, 2024
First-Line Selpercatinib or Chemotherapy and Pembrolizumab in RET Fusion-Positive NSCLC
Published Date: October 21, 2023
Phase 3 Trial of Selpercatinib in Advanced RET-Mutant Medullary Thyroid Cancer.
Published Date: October 21, 2023
LIBRETTO-531: a phase III study of selpercatinib in multikinase inhibitor-Naïve RET-mutant medullary thyroid cancer.
Published Date: August 15, 2022
LIBRETTO-432, a phase III study of adjuvant selpercatinib or placebo in stage IB-IIIA RET fusion-positive non-small-cell lung cancer
Published Date: August 11, 2022

Real-World Outcomes of Selective RET Inhibitor Selpercatinib in the United States: Descriptive, Retrospective Findings from Two Databases
Published Date: November 15, 2024
Initial versus early switch to targeted therapy during first-line treatment among patients with biomarker-positive advanced or metastatic non-small cell lung cancer in the United States
Published Date: September 12, 2023
Real-World Biomarker Testing Patterns in Patients With Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) in a US Community-Based Oncology Practice Setting.
Published Date: March 20, 2023
Costs of biomarker testing among patients with metastatic lung or thyroid cancer in the USA: a real-world commercial claims database study.
Published Date: December 8, 2022
Biomarker Testing for Patients With Advanced/Metastatic Nonsquamous NSCLC in the United States of America, 2015 to 2021
Published Date: August 15, 2022
Diagnostic Value and Cost-Effectiveness of Next Generation Sequencing-Based Testing for Treatment of Patients with Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer in the United States.
Published Date: July 28, 2022
Full article: Biomarker Testing in Patients Diagnosed With Advanced/Metastatic Medullary Thyroid Cancer in the USA
Published Date: May 10, 2022
Diagnostic characteristics, treatment patterns, and clinical outcomes for patients with advanced/metastatic medullary thyroid cancer
Published Date: February 12, 2022

Verzenio® (abemaciclib)

Full Prescribing Information

Recommended phase 2 dose (RP2D) for abemaciclib in combination with irinotecan (IRN) and temozolomide (TMZ) in pediatric patients with relapsed/refractory solid tumors (JPCS Part A).
Published Date: November 4, 2025
A Phase 1 study of abemaciclib plus abiraterone in Japanese patients with metastatic castration-resistant prostate cancer
Published Date: September 9, 2025
Abemaciclib in combination with therapies for patients with metastatic breast cancer: a phase 1b study
Published Date: March 12, 2025
Abemaciclib does not increase the corrected QT interval in healthy participants.
Published Date: June 26, 2023
Abemaciclib in combination with pembrolizumab for HR+, HER2- metastatic breast cancer: Phase 1b study
Published Date: November 5, 2022
Abemaciclib in Combination With Endocrine Therapy for Patients With Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Phase 1b Study.
Published Date: February 10, 2022
Abemaciclib in Combination with Pembrolizumab for Stage IV KRAS-Mutant or Squamous Non-Small Cell Lung Cancer: A Phase 1B Study
Published Date: September 24, 2021

Abemaciclib plus abiraterone in patients with metastatic castration-resistant prostate cancer (CYCLONE 2): a randomised, double-blind, placebo-controlled, phase 3 trial.
Published Date: October 27, 2025
A Signal-Finding Study of Abemaciclib in Heavily Pretreated Patients with Metastatic Castration-Resistant Prostate Cancer: Results from CYCLONE 1.
Published Date: March 29, 2024
Efficacy and safety of abemaciclib alone and with PI3K/mTOR inhibitor LY3023414 or galunisertib versus chemotherapy in previously treated metastatic pancreatic adenocarcinoma: A randomized controlled trial.
Published Date: December 14, 2023
Overall survival and exploratory biomarker analyses of abemaciclib plus trastuzumab with or without fulvestrant vs trastuzumab plus chemotherapy in HR+, HER2+ metastatic breast cancer patients
Published Date: October 31, 2023
Landscape of baseline and acquired genomic alterations in circulating tumor DNA with abemaciclib alone or with endocrine therapy in advanced breast cancer
Published Date: October 27, 2023
An open label, randomized phase 2 trial assessing the impact of food on the tolerability of abemaciclib in patients with advanced breast cancer
Published Date: August 1, 2022
nextMONARCH: Final overall survival analysis of abemaciclib monotherapy or in combination with tamoxifen in patients with HR+, HER2- metastatic breast cancer
Published Date: July 12, 2022

Abemaciclib plus abiraterone in patients with metastatic castration-resistant prostate cancer (CYCLONE 2): a randomised, double-blind, placebo-controlled, phase 3 trial.
Published Date: October 27, 2025
Abemaciclib Plus Fulvestrant in Advanced Breast Cancer Following Progression on CDK4/6 Inhibition: Results from the Phase III postMONARCH trial
Published Date: October 18, 2025
Overall survival with abemaciclib in early breast cancer.
Published Date: October 17, 2025
Abemaciclib Plus Fulvestrant in Patients With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Final Overall Survival Results From MONARCH 2
Published Date: August 5, 2025
Survival benefit from abemaciclib in non-small cell lung cancer by Kirsten rat sarcoma-mutation gene expression subtype: retrospective analysis from the JUNIPER Trial.
Published Date: March 31, 2025
Abemaciclib combined with endocrine therapy as adjuvant treatment for hormone-receptor positive, HER2-, high-risk early breast cancer: 5-year Chinese population analysis of the phase 3 randomized monarchE study
Published Date: October 23, 2024
Abemaciclib plus non-steroidal aromatase inhibitor or fulvestrant in women with HR+/HER2- advanced breast cancer: Final results of the randomized phase III MONARCH plus trial.
Published Date: October 10, 2024
The Impact of Dose Reductions on Efficacy of Adjuvant Abemaciclib for Patients with High-Risk Early Breast Cancer: Analyses from the monarchE Study
Published Date: April 26, 2024
Long-term patient-reported outcomes from monarchE: Abemaciclib plus endocrine therapy as adjuvant therapy for HR+, HER2-, node-positive, high-risk, early breast cancer - European Journal of Cancer
Published Date: January 16, 2024
Adjuvant abemaciclib plus endocrine therapy for high-risk, HR+, HER2-, early breast cancer: results from a preplanned monarchE overall survival.
Published Date: January 9, 2024
Association of Neutrophil-to-Lymphocyte Ratio and Absolute Lymphocyte Count with Clinical Outcomes in Advanced Breast Cancer in the MONARCH 2 Trial
Published Date: November 16, 2023
Efficacy and safety results by menopausal status in monarchE: adjuvant abemaciclib combined with endocrine therapy in patients with HR+, HER2-, node-positive, high-risk early breast cancer.
Published Date: February 8, 2023
Abemaciclib plus endocrine therapy for hormone receptor-positive, HER2-negative, node-positive, high-risk early breast cancer (monarchE): results from a preplanned interim analysis of a randomised, open-label, phase 3 trial
Published Date: December 6, 2022
Adjuvant Abemaciclib Combined with Endocrine Therapy (ET): Efficacy Results in monarchE Cohort 1
Published Date: November 7, 2022
Abemaciclib plus fulvestrant in East Asian women with HR+, HER2- advanced breast cancer: Overall survival from MONARCH 2.
Published Date: October 14, 2022
Treatment With Adjuvant Abemaciclib Plus Endocrine Therapy in Patients With High-risk Early Breast Cancer Who Received Neoadjuvant Chemotherapy: A Prespecified Analysis of the monarchE Randomized Clinical Trial.
Published Date: June 2, 2022
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: safety and patient-reported outcomes from the monarchE study.
Published Date: June 1, 2022
Safety in Japanese advanced breast cancer patients who received abemaciclib in MONARCH 2 and MONARCH 3: assessment of treatment-emergent neutropenia, diarrhea, and increased alanine aminotransferase and aspartate aminotransferase levels
Published Date: March 19, 2022
Clinical Significance of PIK3CA and ESR1 Mutations in Circulating Tumor DNA: Analysis from the MONARCH 2 Study of Abemaciclib plus Fulvestrant.
Published Date: January 31, 2022
A Standardized Investigational Ki-67 Immunohistochemistry Assay Used to Assess High-Risk Early Breast Cancer Patients in the monarchE Phase 3 Clinical Study Identifies a Population With Greater Risk of Disease Recurrence When Treated With Endocrine Therapy Alone.
Published Date: January 26, 2022
Japanese subgroup analysis of the phase 3 MONARCH 3 study of abemaciclib as initial therapy for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer
Published Date: October 18, 2021
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study.
Published Date: October 14, 2021
Abemaciclib plus fulvestrant in hormone receptor positive, HER2-negative advanced breast cancer in premenopausal and perimenopausal women: a subgroup analysis from MONARCH 2 trial
Published Date: August 23, 2021
MONARCH 2: subgroup analysis of patients receiving abemaciclib plus fulvestrant as first-line and second-line therapy for HR+, HER2- advanced breast cancer
Published Date: August 9, 2021
Abemaciclib as initial therapy for advanced breast cancer: MONARCH 3 updated results in prognostic subgroups
Published Date: June 22, 2021

Abemaciclib Persistence in Patients with HR+, HER2−, Node-Positive Early Breast Cancer: a Real-World Analysis | Oncology and Therapy
Published Date: September 22, 2025
Full article: Costs of breast cancer recurrence after initial treatment for HR+, HER2−, high-risk early breast cancer: estimates from SEER-Medicare linked data
Published Date: December 19, 2023
Real-World Analysis of Clinical and Demographic Characteristics, Treatment Patterns, and Outcomes in Predominantly Older Patients with HR+/HER2− Metastatic Breast Cancer Receiving Abemaciclib in Routine Clinical Practice | Drugs - Real World Outcomes
Published Date: August 16, 2023
Treatment patterns and outcomes associated with sequential and non-sequential use of CDK4 & 6 inhibitors in patients with HR+, HER2- MBC in the real world
Published Date: June 14, 2023
Characteristics and Outcomes in US Male Patients (Pts) with Metastatic Breast Cancer (MBC) Receiving Abemaciclib (Abema) in Routine Clinical Practice
Published Date: April 2, 2023
Patient characteristics, treatment patterns, and outcomes of hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer patients prescribed cyclin-dependent kinase 4 and 6 inhibitors: large-scale data analysis using a Japanese claims database
Published Date: November 21, 2022
Real-world patient characteristics, utilization patterns, and outcomes of US patients with HR+/HER2- metastatic breast cancer treated with abemaciclib
Published Date: September 22, 2022
A real-world US study of recurrence risks using combined clinicopathological features in HR-positive, HER2-negative early breast cancer
Published Date: May 25, 2022
Real world incidence and management of adverse events in patients with HR+, HER2- metastatic breast cancer receiving CDK4 and 6 inhibitors in a United States community setting.
Published Date: May 10, 2022
Adjuvant Abemaciclib Combined With Endocrine Therapy for High Risk Early Breast Cancer: Safety and Patient-Reported Outcomes From the monarchE Study
Published Date: March 22, 2022
Breast cancer-specific mortality in early breast cancer as defined by high-risk clinical and pathologic characteristics.
Published Date: March 1, 2022
Treatment Experiences with CDK4&6 Inhibitors Among Women with Metastatic Breast Cancer: A Qualitative Study.
Published Date: November 3, 2021
Prognostic Factors in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative (HR+/HER2-) Advanced Breast Cancer: A Systematic Literature Review
Published Date: August 20, 2021
Real-world clinical profile, treatment patterns and patient-reported outcomes in a subset of HR+/HER2− advanced breast cancer patients with poor prognostic factors: data from an international study
Published Date: August 7, 2021

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