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Welcome to the Lilly Scientific Information Page for ASH 2025

American Society of Hematology

location-single Group Orlando, Florida

Calendar December 6, 2025 - December 9, 2025
side

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Independent-Research Independent Research
External Link Investigator Initiated Research

See how Lilly supports external requests for provision of study drug and/or financial support.

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Disclosures

SATURDAY

DECEMBER 6, 2025, 2:45 p.m ET
  • Disease State: Waldenström Macroglobulinemia
  • Presented by: Chan Cheah
  • Molecule(s): Pirtobrutinib

Pirtobrutinib in Relapsed/Refractory (R/R) Waldenström Macroglobulinemia (WM): Up to 5 Years of Follow-Up from the Phase 1/2 BRUIN Study

Trial(s) Overview:

Phase 1/2 BRUIN Study

Presentation
External Link Abstract

SATURDAY

DECEMBER 6, 2025, 5:30 p.m ET
  • Disease State: Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia
  • Presented by: William Wierda
  • Molecule(s): Pirtobrutinib

Pirtobrutinib in Post-cBTKI CLL/SLL: Final Update from the Phase 1/2 BRUIN Study with More Than 5 Years Follow-Up

Trial(s) Overview:

Phase 1/2 BRUIN Study

Poster
External Link Abstract

SATURDAY

DECEMBER 6, 2025, 5:30 p.m ET
  • Disease State: Mantle-Cell Lymphoma
  • Presented by: Kami Maddocks
  • Molecule(s): Pirtobrutinib

Real-World Treatment Patterns, Patient Characteristics and Outcomes of Initial cBTKi Use in Patients with MCL in the United States

Trial(s) Overview:

Not Applicable

Poster
External Link Abstract

SATURDAY

DECEMBER 6, 2025, 5:30 p.m ET
  • Disease State: Mantle-Cell Lymphoma
  • Presented by: Yuqin Song
  • Molecule(s): Pirtobrutinib

Real-World Characteristics, Treatment Patterns and Outcomes of Patients with Mantle Cell Lymphoma (MCL) After Receiving Covalent Bruton Tyrosine Kinase Inhibitors (cBTKi) in China

Trial(s) Overview:

Not Applicable

Poster
External Link Abstract

SUNDAY

DECEMBER 7, 2025, 5:30 p.m ET
  • Disease State: Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia
  • Presented by: Jennifer Woyach
  • Molecule(s): Pirtobrutinib

Pirtobrutinib vs Ibrutinib in Treatment-Naïve and Relapsed/Refractory CLL/SLL: Results from the First Randomized Phase III Study Comparing a Non-Covalent and Covalent BTK Inhibitor

Trial(s) Overview:

BRUIN CLL-314

Presentation
External Link Abstract

SUNDAY

DECEMBER 7, 2025, 5:30 p.m ET
  • Disease State: Mantle-Cell Lymphoma
  • Presented by: Michael Wang
  • Molecule(s): Pirtobrutinib

Pirtobrutinib in Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL): Final Update from the Phase 1/2 BRUIN Study

Trial(s) Overview:

Phase 1/2 BRUIN Study

Presentation
External Link Abstract

MONDAY

DECEMBER 8, 2025, 6:00 p.m ET
  • Disease State: B-cell Malignancies
  • Presented by: Krish Patel
  • Molecule(s): BAFF-R CD3

BAF_FRontier-1: A First-in-Human Phase 1 Trial of LY4152199, a B-cell Activation Factor Receptor (BAFF-R) T-Cell Engager Bispecific Antibody, in Patients with Previously Treated B-cell Malignancies (Trial in Progress)

Trial(s) Overview:

BAF_FRontier-1

Poster
External Link Abstract

MONDAY

DECEMBER 8, 2025, 6:00 p.m ET
  • Disease State: Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia
  • Presented by: Toby Eyre
  • Molecule(s): Pirtobrutinib

Pirtobrutinib Outcomes in Second Line (2L) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) after First-Line (1L) cBTKi Therapy: A Pooled Analysis from the BRUIN LOXO-BTK-18001 and BRUIN CLL-321 Studies

Trial(s) Overview:

Phase 1/2 BRUIN Study

BRUIN CLL-321

Poster
External Link Abstract

MONDAY

DECEMBER 8, 2025, 6:00 p.m ET
  • Disease State: Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia
  • Presented by: Alexey Danilov
  • Molecule(s): Pirtobrutinib

The Efficacy and Safety of Pirtobrutinib in Patients with CLL/SLL: A Phase 2 Dose Optimization Trial in Progress

Trial(s) Overview:

Not Applicable

Poster
External Link Abstract

MONDAY

DECEMBER 8, 2025, 6:00 p.m ET
  • Disease State: Chronic Lymphocytic Leukemia
  • Presented by: Toby Eyre
  • Molecule(s): Pirtobrutinib

Efficacy of Pirtobrutinib Monotherapy in Treatment-Naïve Chronic Lymphocytic Leukemia: A Bayesian Network Meta-Analysis of Randomized Controlled Trials

Trial(s) Overview:

Not Applicable

Poster
External Link Abstract

TUESDAY

DECEMBER 9, 2025, 8:00 a.m ET
  • Disease State: Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia
  • Presented by: Wojciech Jurczak
  • Molecule(s): Pirtobrutinib

Pirtobrutinib vs Bendamustine Plus Rituximab (BendaR) in Patients With CLL/SLL: First Results from a Randomized Phase III Study Examining a Non-Covalent BTK Inhibitor in Untreated Patients.

Trial(s) Overview:

BRUIN CLL-313

Presentation
External Link Abstract

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