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Type 2 Diabetes Patient Case Simulation
CLINIC-Sim: Simulating a Patient-Centered Approach to Optimize Early Glycemic and Weight Control in Type 2 Diabetes

Learn more about glycemic control and weight management in type 2 diabetes
Shared Decision-Making Resources
Watch an expert video on shared decision-making and download the conversation starter to aid in your patient interactions
These videos were commissioned by Lilly and are intended to be used by HCPs who treat diabetes for medical, scientific and educational purposes.
Video content is not approved for continuing education credit.
Disclosures: Dr. Matt Capehorn
Unpaid:
Paid:
Advisory Boards: Lilly, Boehringer Ingelheim, Novo Nordisk; Speaker fees/travel: Lilly, Boehringer Ingelheim, Novo Nordisk; Research income (RIO): Lilly, Boehringer Ingelheim, Novo Nordisk
Patient Information

- 47-year-old African American female
- Diagnosed with T2D 9 months ago
- HbA1c since diagnosis: 8.7%
- Current treatment: 1000 mg metformin daily at diagnosis
- Followed by registered dietitian/nurse educator
- Prediabetes for 2 years preceding diagnosis, tried to manage with diet and exercise
- Gestational diabetes with her second child
- Hypertension
- Obesity
- Mixed dyslipidemia
- T2D in father, maternal aunt
- CAD in father
- Hypertension in mother and father
- Normal eGFR, normal urine microalbumin
- BMI: 33 kg/m2 (195 lbs)
- Blood pressure: 145/90 mmHg
- Total cholesterol: 210 mg/dL
- LDL cholesterol: 109 mg/dL
- HDL cholesterol: 44 mg/dL
- Triglycerides: 290 mg/dL

9 months since diagnosis
The patient was diagnosed with type 2 diabetes, and her HbA1c was 8.7% at the time. She was started on 1000 mg metformin daily. During that visit, she was advised on lifestyle modifications, including dietary changes to help both her diabetes and hypertension management, as well as recommendations to incorporate exercise. She was encouraged to start a statin for dyslipidemia but was too overwhelmed by her diabetes and declined statin therapy.
At visit 2, her HbA1c decreased to 7.9%. She again declined a statin and agreed to start an ACE inhibitor. Her metformin was titrated to 1500 mg total daily dose.
13 months since diagnosis (4-month follow-up)
- She returns 4 months later.
- She is taking a dose of 1500 mg metformin daily (500 mg in the morning and 1000 mg in the evening) without missing doses. She was not able to tolerate a dose of 1000 mg twice daily. Her HbA1c has decreased to 7.7% from 7.9%, and her body weight remained stable.
- BMI: 33 kg/m2 (195 lbs)
- Blood pressure: 130/85 mmHg
- Total cholesterol: 205 mg/dL
- LDL cholesterol: 110 mg/dL
- HDL cholesterol: 43 mg/dL
- Triglycerides: 260 mg/dL
- She increased her physical activity by parking farther and trying to walk more, but often struggles to find the time to get more exercise in.
- She tries to eat more balanced meals with protein, vegetables and fewer carbohydrates; she finds it difficult to make multiple meals for her family members who prefer to keep to their old dietary routine.
- She is motivated to continue working on lifestyle changes and has agreed to start a statin.
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Question #1
In addition to continuing metformin 1500 mg daily, which of the following may be the next best step?
Option A:
Continue lifestyle modifications – she is very motivated and prefers not to start another medication
Option B:
Start a sulfonylurea and continue lifestyle modifications
Option C:
Start an incretin receptor agonist and continue lifestyle modifications
Option D:
Start a DPP-4 inhibitor
Related Resources
Hear from Dr. Capehorn on collaborating with patients to individualize care.
VV-MED-145674
Patient-Physician Conversation Starter (PDF)
Tips and tricks to initiate patient centric conversations.
VV-MED-145677
Shared Decision-Making (PDF)
Support early glycemic control and weight management through shared decision-making.
VV-MED-148828
VV-MED-144376
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