Skip To Main Content
Lilly
Menu closed
Lilly
  • Account Login / Register
  • Medical Home
  • Medical Education
      • All Therapeutic Areas
        • Alopecia Areata
        • Atopic Dermatitis
        • Dermatology
        • Psoriasis
        • Diabetes
        • Hypoglycemia
        • Inflammatory Bowel Disease
        • Crohn's Disease
        • Ulcerative Colitis
        • Migraine
        • Alzheimer's Disease
        • Cognitive Health
        • Obesity
        • Obstructive Sleep Apnea
        • Breast Cancer - Early
        • Breast Cancer - Metastatic
        • Hematological Malignancy
        • Non-Small Cell Lung Cancer
        • Oncology Precision Medicine
        • Thyroid Cancer
        • Axial Spondyloarthritis
        • Psoriatic Arthritis
        • Resources
      • All Therapeutic Areas
        • Alopecia Areata
        • Atopic Dermatitis
        • Psoriasis
        • Diabetes
        • Hypoglycemia
        • Inflammatory Bowel Disease
        • Cluster Headache
        • Migraine
        • Alzheimer's Disease
        • Cognitive Health
        • Obesity
        • Obstructive Sleep Apnea
        • Breast Cancer - Metastatic
        • Gastrointestinal Cancer
        • Hematological Malignancy
        • Oncology
        • Osteoporosis
        • Rheumatoid Arthritis
        • Resources
  • Independent Medical Education
    • Cardiovascular
      • Alopecia Areata
      • Atopic Dermatitis
      • Psoriasis
      • Diabetes
      • Crohn's Disease
      • Ulcerative Colitis
      • Migraine
      • Alzheimer's Disease
      • Obesity
      • Obstructive Sleep Apnea
      • Breast Cancer
      • Gastrointestinal Cancer
      • Hematological Malignancy
      • Non-Small Cell Lung Cancer
      • Oncology
      • Oncology Precision Medicine
      • Prostate Cancer
      • Axial Spondyloarthritis
      • Psoriatic Arthritis
  • Chat Contact Us
Lilly

You are now leaving the Lilly Medical Education website

The link you clicked on will take you to a site maintained by a third party, which is solely responsible for its content. Lilly USA, LLC does not control, influence, or endorse this site, and the opinions, claims, or comments expressed on this site should not be attributed to Lilly USA, LLC. Lilly USA, LLC is not responsible for the privacy policy of any third-party websites. We encourage you to read the privacy policy of every website you visit.
Click "Continue" to proceed or "Return" to return to Lilly Medical Education.

OBSERVE

Loading icon

Study Overview

Patient Perspectives

HCP Perspectives

HCP Perspectives

OBSERVE is a study evaluating the attitudes of key stakeholders in the US about obesity and its effective therapy.


Qualitative Phone Interview Results: HCP Perspective1


HCP and Patient Perceptions Toward Obesity and its Treatment: Obesity as a Disease
Bar graph showing HCP and patient perceptions toward obesity and its treatment as a disease.

*Respondents ranked their level of agreement from “0: completely disagree” to “10: completely agree.”

chevron-filled-down Image description
HCPs who were not specialists in obesity reported:

  • Prioritizing obesity treatment less than other conditions that they perceived as being easier to treat
  • Being unaware of current treatment guidelines for obesity
  • Referring patients with obesity to other specialists, clinics, or programs due to perceived lack of counseling resources for obesity within their practice
Quote #1. Read the image description
chevron-filled-down Image description

The majority of surveyed HCPs did not view AOM use alone as a durable solution and indicated that lifestyle changes were required for long-term maintenance of weight loss.


Quote #2. Read the image description.
chevron-filled-down Image description

Key areas of agreement between patients and HCPs:

Perceptions of weight loss

  • AOMs can be a useful short-term “kickstart”
  • Weight management programs can help
  • AOMs are not a durable solution


Quote #3. Read the image description.
chevron-filled-down Image description

Key areas of disagreement between patients and HCPs:

Perceptions of obesity

  • HCPs see obesity as a long-term disease
  • People with obesity see it as a self-modifiable condition

Quantitative Web-Based Survey Results: HCP Perspective2

Respondents were asked to rank their level of agreement or concern with statements referring to perceptions and treatment of obesity and AOMs.

When ranking agreement, the provided options were “strongly agree,” “agree,” “neutral,” “disagree,” and “strongly disagree.” For the following data:

  • “Agree” includes those who selected “strongly agree” or “agree”
  • “Disagree” includes those who selected “strongly disagree” or “disagree”


When ranking concern, the provided options were “very concerned,” “quite a bit concerned,” “moderately concerned,” “a little concerned,” and “not at all concerned.” For the following data:

  • “Concerned” includes those who selected “very concerned” or “quite a bit concerned”

HCPs were given statements regarding perceptions of obesity and were asked to provide their level of agreement or disagreement with each one.2


HCPs’ most agreed and disagreed statements.
chevron-filled-down Image description
HCPs were asked to rank their level of agreement or disagreement with different beliefs about AOMs2

HCPs disagreed with:

  • AOMs are a short-term fix without lasting benefits (26.6%)
  • The safety history of prior AOMs makes me cautious to consider them (26.0%)
  • I need more long-term safety data regarding AOMs for them to become a part of my treatment repertoire (23.0%)

HCPs agreed with:

  • I am looking forward to new AOM options being available on the market (83.9%)
  • Sustained weight loss will still require a lifestyle change (eg, diet, exercise) even when taking an AOM (80.8%)
  • There is a need for more effective AOM options than those currently available, including new-generation AOMs (75.2%)

Data on the respondents’ concerns about hypothetical new-generation FDA-approved AOMs.
chevron-filled-down Image description

Factors that reduce HCP willingness to recommend a hypothetical new-generation AOM2

  • Patient is elderly (34.4%)
  • Involves daily at-home injections (40.5%)
  • Involves weekly at-home injections (23.9%)

Factors that increase HCP willingness to recommend a hypothetical new-generation AOM2

  • Worked for other patients (87.1%)
  • Costs covered by insurance (85.7%)
  • Helps address other illnesses associated with obesity (83.7%)

Summary

The OBSERVE study determined that HCPs perceive obesity as a disease with significant impact on long-term health.1 HCPs did not see AOMs as a durable weight loss solution and expressed concerns regarding their cost and potential side effects.1,2 However, the surveyed HCPs were interested in combining AOMs with lifestyle modification to “kickstart” weight loss.2 HCPs expressed interest in upcoming AOMs, especially those that can treat multiple conditions.2 Please refer to the cited references for complete results.

For more information about the HCP perspectives identified in the OBSERVE study, check out the video below.

References

  1. Ard JD, Kaplan LM, Dunn JP, et al. Pharmacotherapy use in obesity care: divergence among health care providers and persons with obesity. Poster presented at ObesityWeek; November 1, 2021; virtual meeting.
  2. Kahan S, Kumar RB, Ahmad NN, et al. Healthcare providers’ perceptions of anti-obesity medications: results from the OBSERVE study. Poster presented at American Association of Clinical Endocrinologists (AACE) 32nd Annual Meeting; May 6, 2022; Seattle, WA.

VV-MED-141930

Please rate your satisfaction with the content on the following statements:

Very Dissatisfied

Dissatisfied

Neutral

Satisfied

Very Satisfied

Credibility of information
Credibility of information
Relevance of the information to my needs
Relevance of the information to my needs
Confidence to implement the learnings in my clinical practice
Confidence to implement the learnings in my clinical practice

Please rate your satisfaction with the content on the following statements:

Credibility of information
Credibility of information
Very Satisfied
Very Dissatisfied
Relevance of the information to my needs
Relevance of the information to my needs
Very Satisfied
Very Dissatisfied
Confidence to implement the learnings in my clinical practice
Confidence to implement the learnings in my clinical practice
Very Satisfied
Very Dissatisfied
  • Copyright
  • Terms of Use
  • Privacy Statement
  • Consumer Health Privacy Notice
  • Accessibility Statement
  • Sitemap

To speak to customer support:
Call (XXX) XXX-XXXX

This site is intended for US Healthcare Professionals only.

4.4.54 05/2025 | GLOOTH00001 04/2015 | © Lilly USA, LLC 2025. All rights reserved.

Product names listed above are trademarks or registered trademarks owned by or licensed to Eli Lilly and Company, its subsidiaries, or affiliates

California Consumer Privacy Act (CCPA) Opt-Out Icon Your Privacy Choices
Cookie Settings
Facebook X LinkedIn
Lilly